Human Serine Racemase: Key Residues/Active Site Motifs and Their Relation to Enzyme Function

Serine racemase (SR) is the first racemase enzyme to be identified in human biology and converts L-serine to D-serine, an important neuronal signaling molecule that serves as a co-agonist of the NMDA (N-methyl-D-aspartate) receptor. This overview describes key molecular features of the enzyme, focus...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Graham, Danielle L., Beio, Matthew L., Nelson, David L., Berkowitz, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424897/
https://ncbi.nlm.nih.gov/pubmed/30918891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00008
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