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Induction of serine racemase expression and D-serine release from microglia by amyloid β-peptide

BACKGROUND: Roles for excitotoxicity and inflammation in Alzheimer's disease have been hypothesized. Proinflammatory stimuli, including amyloid β-peptide (Aβ), elicit a release of glutamate from microglia. We tested the possibility that a coagonist at the NMDA class of glutamate receptors, D-serine,...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Principais autores: Wu, Sheng-Zhou, Bodles, Angela M, Porter, Mandy M, Griffin, W Sue T, Basile, Anthony S, Barger, Steven W
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC483052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15285800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1742-2094-1-2
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