Induction of serine racemase expression and D-serine release from microglia by amyloid β-peptide

BACKGROUND: Roles for excitotoxicity and inflammation in Alzheimer's disease have been hypothesized. Proinflammatory stimuli, including amyloid β-peptide (Aβ), elicit a release of glutamate from microglia. We tested the possibility that a coagonist at the NMDA class of glutamate receptors, D-serine,...

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Pubblicato in:	J Neuroinflammation
Autori principali:	Wu, Sheng-Zhou, Bodles, Angela M, Porter, Mandy M, Griffin, W Sue T, Basile, Anthony S, Barger, Steven W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2004
Soggetti:	Research
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC483052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15285800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1742-2094-1-2
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