Induction of serine racemase expression and D-serine release from microglia by amyloid β-peptide

BACKGROUND: Roles for excitotoxicity and inflammation in Alzheimer's disease have been hypothesized. Proinflammatory stimuli, including amyloid β-peptide (Aβ), elicit a release of glutamate from microglia. We tested the possibility that a coagonist at the NMDA class of glutamate receptors, D-se...

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Hlavní autoři: Wu, Sheng-Zhou, Bodles, Angela M, Porter, Mandy M, Griffin, W Sue T, Basile, Anthony S, Barger, Steven W
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC483052/
https://ncbi.nlm.nih.gov/pubmed/15285800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-1-2
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