Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis

Motoneuron loss and reactive astrocytosis are pathological hallmarks of amyotrophic lateral sclerosis (ALS), a paralytic neurodegenerative disease that can be triggered by mutations in Cu-Zn superoxide dismutase (SOD1). Dysfunctional astrocytes contribute to ALS pathogenesis, inducing motoneuron dam...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Díaz-Amarilla, Pablo, Olivera-Bravo, Silvia, Trias, Emiliano, Cragnolini, Andrea, Martínez-Palma, Laura, Cassina, Patricia, Beckman, Joseph, Barbeito, Luis
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207668/
https://ncbi.nlm.nih.gov/pubmed/22010221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110689108
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk