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Heterogeneity and dynamics in the assembly of the Heat Shock Protein 90 chaperone complexes

The Hsp90 cycle depends on the coordinated activity of a range of cochaperones, including Hop, Hsp70 and peptidyl-prolyl isomerases such as FKBP52. Using mass spectrometry, we investigate the order of addition of these cochaperones and their effects on the stoichiometry and composition of the result...

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Bibliografski detalji
Glavni autori: Ebong, Ima-obong, Morgner, Nina, Zhou, Min, Saraiva, Marco A., Daturpalli, Soumya, Jackson, Sophie E., Robinson, Carol V.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207645/
https://ncbi.nlm.nih.gov/pubmed/22011577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106261108
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