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Heterogeneity and dynamics in the assembly of the Heat Shock Protein 90 chaperone complexes
The Hsp90 cycle depends on the coordinated activity of a range of cochaperones, including Hop, Hsp70 and peptidyl-prolyl isomerases such as FKBP52. Using mass spectrometry, we investigate the order of addition of these cochaperones and their effects on the stoichiometry and composition of the result...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207645/ https://ncbi.nlm.nih.gov/pubmed/22011577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106261108 |
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