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Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity
Hsp90 is an essential and highly conserved modular molecular chaperone whose N and middle domains are separated by a disordered region termed the charged linker. Although its importance has been previously disregarded, because a minimal linker length is sufficient for Hsp90 activity, the evolutionar...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287002/ https://ncbi.nlm.nih.gov/pubmed/22315411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114414109 |
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