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Crowding Activates Heat Shock Protein 90

Hsp90 is a dimeric ATP-dependent chaperone involved in the folding, maturation, and activation of diverse target proteins. Extensive in vitro structural analysis has led to a working model of Hsp90's ATP-driven conformational cycle. An implicit assumption is that dilute experimental conditions...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Halpin, Jackson C., Huang, Bin, Sun, Ming, Street, Timothy O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813586/
https://ncbi.nlm.nih.gov/pubmed/26797120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702928
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