Impact of a Glycogen Phosphorylase Inhibitor and Metformin on Basal and Glucagon-Stimulated Hepatic Glucose Flux in Conscious Dogs

The effects of a glycogen phosphorylase inhibitor (GPI) and metformin (MT) on hepatic glucose fluxes (μmol · kg(−1) · min(−1)) in the presence of basal and 4-fold basal levels of plasma glucagon were investigated in 18-h fasted conscious dogs. Compared with the vehicle treatment, GPI infusion suppre...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Torres, Tracy P., Sasaki, Noriyasu, Donahue, E. Patrick, Lacy, Brooks, Printz, Richard L., Cherrington, Alan D., Treadway, Judith L., Shiota, Masakazu
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207486/
https://ncbi.nlm.nih.gov/pubmed/21363927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.177899
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares