Ouabain Binding Site in a Functioning Na(+)/K(+) ATPase

The Na(+)/K(+) ATPase is an almost ubiquitous integral membrane protein within the animal kingdom. It is also the selective target for cardiotonic derivatives, widely prescribed inhibitors for patients with heart failure. Functional studies revealed that ouabain-sensitive residues distributed widely...

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Bibliografiska uppgifter
Huvudupphovsmän: Sandtner, Walter, Egwolf, Bernhard, Khalili-Araghi, Fatemeh, Sánchez-Rodríguez, Jorge E., Roux, Benoit, Bezanilla, Francisco, Holmgren, Miguel
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Molecular Biophysics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207469/
https://ncbi.nlm.nih.gov/pubmed/21911500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267682
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