Ouabain Binding Site in a Functioning Na(+)/K(+) ATPase

The Na(+)/K(+) ATPase is an almost ubiquitous integral membrane protein within the animal kingdom. It is also the selective target for cardiotonic derivatives, widely prescribed inhibitors for patients with heart failure. Functional studies revealed that ouabain-sensitive residues distributed widely...

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Bibliografiske detaljer
Main Authors: Sandtner, Walter, Egwolf, Bernhard, Khalili-Araghi, Fatemeh, Sánchez-Rodríguez, Jorge E., Roux, Benoit, Bezanilla, Francisco, Holmgren, Miguel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207469/
https://ncbi.nlm.nih.gov/pubmed/21911500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267682
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