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Ouabain Binding Site in a Functioning Na(+)/K(+) ATPase
The Na(+)/K(+) ATPase is an almost ubiquitous integral membrane protein within the animal kingdom. It is also the selective target for cardiotonic derivatives, widely prescribed inhibitors for patients with heart failure. Functional studies revealed that ouabain-sensitive residues distributed widely...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207469/ https://ncbi.nlm.nih.gov/pubmed/21911500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267682 |
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