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Ouabain Binding Site in a Functioning Na(+)/K(+) ATPase

The Na(+)/K(+) ATPase is an almost ubiquitous integral membrane protein within the animal kingdom. It is also the selective target for cardiotonic derivatives, widely prescribed inhibitors for patients with heart failure. Functional studies revealed that ouabain-sensitive residues distributed widely...

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Autors principals: Sandtner, Walter, Egwolf, Bernhard, Khalili-Araghi, Fatemeh, Sánchez-Rodríguez, Jorge E., Roux, Benoit, Bezanilla, Francisco, Holmgren, Miguel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207469/
https://ncbi.nlm.nih.gov/pubmed/21911500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267682
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