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The Physiological Significance of the Cardiotonic Steroid/Ouabain-Binding Site of the Na,K-ATPase
The Na,K-ATPase is the membrane “pump” that generates the Na(+) and K(+) gradients across the plasma membrane that drives many physiological processes. This enzyme is highly sensitive to inhibition by cardiotonic steroids, most notably the digitalis/ouabain class of compounds, which have been used f...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079441/ https://ncbi.nlm.nih.gov/pubmed/20148682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021909-135725 |
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