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The Physiological Significance of the Cardiotonic Steroid/Ouabain-Binding Site of the Na,K-ATPase

The Na,K-ATPase is the membrane “pump” that generates the Na(+) and K(+) gradients across the plasma membrane that drives many physiological processes. This enzyme is highly sensitive to inhibition by cardiotonic steroids, most notably the digitalis/ouabain class of compounds, which have been used f...

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Bibliografiske detaljer
Hovedforfatter: Lingrel, Jerry B
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079441/
https://ncbi.nlm.nih.gov/pubmed/20148682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021909-135725
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