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Allele-dependent Processing Pathways Generate the Endogenous Human Leukocyte Antigen (HLA) Class I Peptide Repertoire in Transporters Associated with Antigen Processing (TAP)-deficient Cells

The transporters associated with antigen processing (TAP) allow the supply of peptides derived from the cytosol to translocate to the endoplasmic reticulum, where they complex with nascent human leukocyte antigen (HLA) class I molecules. However, infected and tumor cells with TAP molecules blocked o...

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Autori principali: Lorente, Elena, García, Ruth, López, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207402/
https://ncbi.nlm.nih.gov/pubmed/21914809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281808
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