Role of Metalloproteases in Vaccinia Virus Epitope Processing for Transporter Associated with Antigen Processing (TAP)-independent Human Leukocyte Antigen (HLA)-B7 Class I Antigen Presentation

The transporter associated with antigen processing (TAP) translocates the viral proteolytic peptides generated by the proteasome and other proteases in the cytosol to the endoplasmic reticulum lumen. There, they complex with nascent human leukocyte antigen (HLA) class I molecules, which are subseque...

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Detalhes bibliográficos
Main Authors: Lorente, Elena, García, Ruth, Mir, Carmen, Barriga, Alejandro, Lemonnier, François A., Ramos, Manuel, López, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323003/
https://ncbi.nlm.nih.gov/pubmed/22298786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314856
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