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Allele-dependent Processing Pathways Generate the Endogenous Human Leukocyte Antigen (HLA) Class I Peptide Repertoire in Transporters Associated with Antigen Processing (TAP)-deficient Cells

The transporters associated with antigen processing (TAP) allow the supply of peptides derived from the cytosol to translocate to the endoplasmic reticulum, where they complex with nascent human leukocyte antigen (HLA) class I molecules. However, infected and tumor cells with TAP molecules blocked o...

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Detalhes bibliográficos
Main Authors: Lorente, Elena, García, Ruth, López, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207402/
https://ncbi.nlm.nih.gov/pubmed/21914809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281808
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