Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules

Major histocompatibility complex class I (MHCI) glycoproteins present cytosolic peptides to CD8+ T cells and regulate NK cell activity. Their heavy chains (HC) are expressed from up to three MHC gene loci (human leukocyte antigen [HLA]-A, -B, and -C in humans), whose extensive polymorphism maps pred...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Prevosto, Claudia, Usmani, M. Farooq, McDonald, Sarah, Gumienny, Aleksandra M., Key, Tim, Goodman, Reyna S., Gaston, J. S. Hill, Deery, Michael J., Busch, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987023/
https://ncbi.nlm.nih.gov/pubmed/27529174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161011
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