Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules

Major histocompatibility complex class I (MHCI) glycoproteins present cytosolic peptides to CD8+ T cells and regulate NK cell activity. Their heavy chains (HC) are expressed from up to three MHC gene loci (human leukocyte antigen [HLA]-A, -B, and -C in humans), whose extensive polymorphism maps pred...

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Vydáno v:PLoS One
Hlavní autoři: Prevosto, Claudia, Usmani, M. Farooq, McDonald, Sarah, Gumienny, Aleksandra M., Key, Tim, Goodman, Reyna S., Gaston, J. S. Hill, Deery, Michael J., Busch, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987023/
https://ncbi.nlm.nih.gov/pubmed/27529174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161011
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