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Characterization of Mg(2+) Inhibition of Mitochondrial Ca(2+) Uptake by a Mechanistic Model of Mitochondrial Ca(2+) Uniporter
Ca(2+) is an important regulatory ion and alteration of mitochondrial Ca(2+) homeostasis can lead to cellular dysfunction and apoptosis. Ca(2+) is transported into respiring mitochondria via the Ca(2+) uniporter, which is known to be inhibited by Mg(2+). This uniporter-mediated mitochondrial Ca(2+)...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207172/ https://ncbi.nlm.nih.gov/pubmed/22067144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.029 |
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