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Characterization of Membrane Potential Dependency of Mitochondrial Ca(2+) Uptake by an Improved Biophysical Model of Mitochondrial Ca(2+) Uniporter

Mitochondrial Ca(2+) uniporter is the primary influx pathway for Ca(2+) into respiring mitochondria, and hence plays a key role in mitochondrial Ca(2+) homeostasis. Though the mechanism of extra-matrix Ca(2+) dependency of mitochondrial Ca(2+) uptake has been well characterized both experimentally a...

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Detalhes bibliográficos
Main Authors: Pradhan, Ranjan K., Qi, Feng, Beard, Daniel A., Dash, Ranjan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951907/
https://ncbi.nlm.nih.gov/pubmed/20949039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013278
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