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Analysis of cardiac mitochondrial Na(+)–Ca(2+) exchanger kinetics with a biophysical model of mitochondrial Ca(2+) handing suggests a 3: 1 stoichiometry
Calcium is a key ion and is known to mediate signalling pathways between cytosol and mitochondria and modulate mitochondrial energy metabolism. To gain a quantitative, biophysical understanding of mitochondrial Ca(2+) regulation, we developed a thermodynamically balanced model of mitochondrial Ca(2+...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Blackwell Science Inc
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538784/ https://ncbi.nlm.nih.gov/pubmed/18467367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.151977 |
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