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7-Dehydrocholesterol reductase activity is independent of cytochrome P450 reductase

7-Dehydrocholesterol reductase (DHCR7) catalyzes the final step in cholesterol synthesis. The enzyme utilizes NADPH as a source of electrons and has been reported to require NADPH-cytochrome P450 reductase (POR) as its redox partner. To test this hypothesis, microsomes were prepared from the livers...

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Detalhes bibliográficos
Main Authors: Zou, Ling, Li, Li, Porter, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207014/
https://ncbi.nlm.nih.gov/pubmed/21762780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.06.011
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