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Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1
Cytochrome P450 (P450 or CYP) 46A1 is expressed in brain and has been characterized by its ability to oxidize cholesterol to 24S-hydroxycholesterol. In addition, the same enzyme is known to further oxidize 24S-hydroxycholesterol to the 24,25- and 24,27-dihydroxy products, as well as to catalyze side...
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| Yayımlandı: | J Lipid Res |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Biochemistry and Molecular Biology
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617353/ https://ncbi.nlm.nih.gov/pubmed/25017465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M051508 |
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