P50, the Small Subunit of DNA Polymerase Delta, Is Required for Mediation of the Interaction of Polymerase Delta Subassemblies with PCNA

Mammalian DNA polymerase δ (pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and various DNA repair processes. Its function as a chromosomal DNA polymerase is dependent on the association with proliferating cell nuclear antigen (PCNA) which functions as a molecula...

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Main Authors: Wang, Yujue, Zhang, Qian, Chen, Huiqing, Li, Xiao, Mai, Weijun, Chen, Keping, Zhang, Sufang, Lee, Ernest Y. C., Lee, Marietta Y. W. T., Zhou, Yajing
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206906/
https://ncbi.nlm.nih.gov/pubmed/22073260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027092
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