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Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation

Previous experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP. Here we use a genome-scale model of human cell metabolism to inves...

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Библиографические подробности
Главные авторы: Vazquez, Alexei, Markert, Elke K., Oltvai, Zoltán N.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206798/
https://ncbi.nlm.nih.gov/pubmed/22073143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025881
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