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Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation

Previous experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP. Here we use a genome-scale model of human cell metabolism to inves...

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Bibliografische gegevens
Hoofdauteurs: Vazquez, Alexei, Markert, Elke K., Oltvai, Zoltán N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206798/
https://ncbi.nlm.nih.gov/pubmed/22073143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025881
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