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Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation

Previous experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP. Here we use a genome-scale model of human cell metabolism to inves...

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Detalhes bibliográficos
Main Authors: Vazquez, Alexei, Markert, Elke K., Oltvai, Zoltán N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206798/
https://ncbi.nlm.nih.gov/pubmed/22073143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025881
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