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Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease

We recently reported that expression levels of tumor necrosis factor (TNF) receptors, TNFR1 and TNFR2, are significantly changed in the brains and cerebrospinal fluid (CSF) with Alzheimer's disease (AD). Moreover, we also found that, in an Alzheimer's mouse model, genetic deletion of TNF r...

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Detalhes bibliográficos
Main Authors: Jiang, Hong, Hampel, Harald, Prvulovic, David, Wallin, Anders, Blennow, Kaj, Li, Rena, Shen, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206445/
https://ncbi.nlm.nih.gov/pubmed/21978728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-69
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