Increased Plasma TACE Activity in Subjects with Mild Cognitive Impairment and Patients with Alzheimer’s Disease

Evidence suggests that the tumor necrosis factor receptor (TNFR)-signaling pathway contributes to the pathogenesis of Alzheimer’s disease (AD). TNF-α converting enzyme (TACE/ADAM-17) can cleave both pro-TNF-α and TNF receptors. Recently, we have shown that TACE activity in the cerebrospinal fluid (C...

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Detaylı Bibliyografya
Asıl Yazarlar: Sun, Qiying, Hampel, Harald, Blennow, Kaj, Lista, Simone, Levey, Allan, Tang, Beisha, Li, Rena, Shen, Yong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153789/
https://ncbi.nlm.nih.gov/pubmed/24685635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-140177
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