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Increased Plasma TACE Activity in Subjects with Mild Cognitive Impairment and Patients with Alzheimer’s Disease
Evidence suggests that the tumor necrosis factor receptor (TNFR)-signaling pathway contributes to the pathogenesis of Alzheimer’s disease (AD). TNF-α converting enzyme (TACE/ADAM-17) can cleave both pro-TNF-α and TNF receptors. Recently, we have shown that TACE activity in the cerebrospinal fluid (C...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153789/ https://ncbi.nlm.nih.gov/pubmed/24685635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-140177 |
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