Elevated Membrane Attack Complex in Human Choroid With High Risk Complement Factor H Genotypes

Data from human genetics, histopathology, and animal models reveal a major role for the complement system in the development of age-related macular degeneration (AMD). Genetic variations in the complement factor H (CFH) gene are associated with an elevated risk of AMD. In this study we sought to det...

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Main Authors: Mullins, Robert F., Dewald, Aaron D., Streb, Luan M., Wang, Kai, Kuehn, Markus H., Stone, Edwin M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206185/
https://ncbi.nlm.nih.gov/pubmed/21729696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.06.015
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