The Temporal Order of Genetic and Pathway Alterations in Tumorigenesis

Cancer evolves through the accumulation of mutations, but the order in which mutations occur is poorly understood. Inference of a temporal ordering on the level of genes is challenging because clinically and histologically identical tumors often have few mutated genes in common. This heterogeneity m...

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Detaylı Bibliyografya
Asıl Yazarlar: Gerstung, Moritz, Eriksson, Nicholas, Lin, Jimmy, Vogelstein, Bert, Beerenwinkel, Niko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206070/
https://ncbi.nlm.nih.gov/pubmed/22069497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027136
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