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A Peptide of SPARC Interferes with the Interaction between Caspase8 and Bcl2 to Resensitize Chemoresistant Tumors and Enhance Their Regression In Vivo

SPARC, a matricellular protein with tumor suppressor properties in certain human cancers, was initially identified in a genome-wide analysis of differentially expressed genes in chemotherapy resistance. Its exciting new role as a potential chemosensitizer arises from its ability to augment the apopt...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rahman, Mahbuba, Chan, Annie P. K., Tai, Isabella T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206029/
https://ncbi.nlm.nih.gov/pubmed/22069448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026390
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