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Inhibition of COX-2 in Colon Cancer Modulates Tumor Growth and MDR-1 Expression to Enhance Tumor Regression in Therapy-Refractory Cancers In Vivo

Higher cyclooxygenase 2 (COX-2) expression is often observed in aggressive colorectal cancers (CRCs). Here, we attempt to examine the association between COX-2 expression in therapy-refractory CRC, how it affects chemosensitivity, and whether, in primary tumors, it is predictive of clinical outcomes...

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Detalhes bibliográficos
Main Authors: Rahman, Mahbuba, Selvarajan, Krithika, Hasan, Mohammad R, Chan, Annie P, Jin, Chaoyang, Kim, Jieun, Chan, Simon K, Le, Nhu D, Kim, Young-Bae, Tai, Isabella T
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421958/
https://ncbi.nlm.nih.gov/pubmed/22904679
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