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Infectious Prion Protein Alters Manganese Transport and Neurotoxicity in a Cell Culture Model of Prion Disease

Protein misfolding and aggregation are considered key features of many neurodegenerative diseases, but biochemical mechanisms underlying protein misfolding and the propagation of protein aggregates are not well understood. Prion disease is a classical neurodegenerative disorder resulting from the mi...

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Autori principali: Martin, Dustin P., Anantharam, Vellareddy, Jin, Huajun, Witte, Travis, Houk, Robert, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205977/
https://ncbi.nlm.nih.gov/pubmed/21871919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2011.07.008
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