A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma()

Glycans are cell-type specific, post-translational protein modifications that are modulated during developmental and disease processes. As such, glycoproteins are attractive biomarker candidates. Here, we describe a mass spectrometry-based workflow that incorporates lectin affinity chromatography to...

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Detalhes bibliográficos
Main Authors: Drake, Penelope M., Schilling, Birgit, Niles, Richard K., Braten, Miles, Johansen, Eric, Liu, Haichuan, Lerch, Michael, Sorensen, Dylan J., Li, Bensheng, Allen, Simon, Hall, Steven C., Witkowska, H. Ewa, Regnier, Fred E., Gibson, Bradford W., Fisher, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205961/
https://ncbi.nlm.nih.gov/pubmed/20705048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.08.010
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