A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma()

Glycans are cell-type specific, post-translational protein modifications that are modulated during developmental and disease processes. As such, glycoproteins are attractive biomarker candidates. Here, we describe a mass spectrometry-based workflow that incorporates lectin affinity chromatography to...

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Main Authors: Drake, Penelope M., Schilling, Birgit, Niles, Richard K., Braten, Miles, Johansen, Eric, Liu, Haichuan, Lerch, Michael, Sorensen, Dylan J., Li, Bensheng, Allen, Simon, Hall, Steven C., Witkowska, H. Ewa, Regnier, Fred E., Gibson, Bradford W., Fisher, Susan J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205961/
https://ncbi.nlm.nih.gov/pubmed/20705048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.08.010
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