A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma()

Glycans are cell-type specific, post-translational protein modifications that are modulated during developmental and disease processes. As such, glycoproteins are attractive biomarker candidates. Here, we describe a mass spectrometry-based workflow that incorporates lectin affinity chromatography to...

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Bibliografiske detaljer
Main Authors: Drake, Penelope M., Schilling, Birgit, Niles, Richard K., Braten, Miles, Johansen, Eric, Liu, Haichuan, Lerch, Michael, Sorensen, Dylan J., Li, Bensheng, Allen, Simon, Hall, Steven C., Witkowska, H. Ewa, Regnier, Fred E., Gibson, Bradford W., Fisher, Susan J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205961/
https://ncbi.nlm.nih.gov/pubmed/20705048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.08.010
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