Sweetening the pot: adding glycosylation to the biomarker discovery equation

BACKGROUND: Cancer has profound effects on gene expression, including a cell’s glycosylation machinery. Thus, tumors produce glycoproteins that carry oligosaccharides with structures that are markedly different from the same protein produced by a normal cell. A single protein can have many glycosyla...

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Autors principals: Drake, Penelope M., Cho, Wonryeon, Li, Bensheng, Prakobphol, Akraporn, Johansen, Eric, Anderson, N. Leigh, Regnier, Fred E., Gibson, Bradford W., Fisher, Susan J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849286/
https://ncbi.nlm.nih.gov/pubmed/19959616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2009.136333
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