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Distinct PGE(2)-responder and non-responder phenotypes in human mast cell populations: “All or nothing” enhancement of antigen-dependent mediator release

Reports indicate that prostaglandin (PG)E(2) markedly enhances antigen-mediated degranulation in mouse bone marrow-derived mast cells (BMMCs) but not in human mast cells (HuMCs). We have examined the underlying mechanism(s) for this disparity in HuMCs derived from the peripheral blood of multiple do...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kuehn, Hye Sun, Jung, Mi-Yeon, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205336/
https://ncbi.nlm.nih.gov/pubmed/21798286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2011.07.002
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