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Distinct PGE(2)-responder and non-responder phenotypes in human mast cell populations: “All or nothing” enhancement of antigen-dependent mediator release
Reports indicate that prostaglandin (PG)E(2) markedly enhances antigen-mediated degranulation in mouse bone marrow-derived mast cells (BMMCs) but not in human mast cells (HuMCs). We have examined the underlying mechanism(s) for this disparity in HuMCs derived from the peripheral blood of multiple do...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205336/ https://ncbi.nlm.nih.gov/pubmed/21798286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2011.07.002 |
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