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Interleukin-5 receptor α levels in patients with marked eosinophilia or mastocytosis

BACKGROUND: Interleukin (IL)-5 plays a central role in the development and maintenance of eosinophilia and eosinophil activation in a wide variety of eosinophilic disorders. Although IL-5, IL-3 and GM-CSF can modulate expression of IL-5 receptor α (IL-5Rα) on eosinophils in vitro, little is known ab...

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Autors principals: Wilson, Todd M., Maric, Irina, Shukla, Juhi, Brown, Margaret, Santos, Carlo, Simakova, Olga, Khoury, Paneez, Fay, Michael P., Kozhich, Alexander, Kolbeck, Roland, Metcalfe, Dean D., Klion, Amy D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205313/
https://ncbi.nlm.nih.gov/pubmed/21762978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.05.032
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