Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen

Thrombosis and cardiovascular disease (CVD) represent major causes of morbidity and mortality. Low androgen correlates with higher incidence of CVD/thrombosis. Tissue Factor Pathway Inhibitor (TFPI) is the major inhibitor of tissue factor-factor VIIa (TF-FVIIa)–dependent FXa generation. Because endo...

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Autori principali: Lupu, Cristina, Zhu, Hua, Popescu, Narcis I., Wren, Jonathan D., Lupu, Florea
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204913/
https://ncbi.nlm.nih.gov/pubmed/21868574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-355370
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