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Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen

Thrombosis and cardiovascular disease (CVD) represent major causes of morbidity and mortality. Low androgen correlates with higher incidence of CVD/thrombosis. Tissue Factor Pathway Inhibitor (TFPI) is the major inhibitor of tissue factor-factor VIIa (TF-FVIIa)–dependent FXa generation. Because endo...

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Bibliografiske detaljer
Main Authors: Lupu, Cristina, Zhu, Hua, Popescu, Narcis I., Wren, Jonathan D., Lupu, Florea
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204913/
https://ncbi.nlm.nih.gov/pubmed/21868574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-355370
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