Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane

Diabetes mellitus is associated with platelet hyperactivity, which leads to increased morbidity and mortality from cardiovascular disease. This is coupled with enhanced levels of thromboxane (TX), an eicosanoid that facilitates platelet aggregation. Although intensely studied, the mechanism underlyi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tang, Wai Ho, Stitham, Jeremiah, Gleim, Scott, Di Febbo, Concetta, Porreca, Ettore, Fava, Cristiano, Tacconelli, Stefania, Capone, Marta, Evangelista, Virgilio, Levantesi, Giacomo, Wen, Li, Martin, Kathleen, Minuz, Pietro, Rade, Jeffrey, Patrignani, Paola, Hwa, John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204848/
https://ncbi.nlm.nih.gov/pubmed/22005299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59291
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky