Human Thromboxane A(2) Receptor Genetic Variants: In Silico, In Vitro and “In Platelet” Analysis

Thromboxane and its receptor have emerged as key players in modulating vascular thrombotic events. Thus, a dysfunctional hTP genetic variant may protect against (hypoactivity) or promote (hyperactivity) vascular events, based upon its activity on platelets. After extensive in silico analysis, six hT...

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Bibliografiske detaljer
Main Authors: Gleim, Scott, Stitham, Jeremiah, Tang, Wai Ho, Li, Hong, Douville, Karen, Chelikani, Prashen, J.Rade, Jeffrey, Martin, Kathleen A., Hwa, John
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696120/
https://ncbi.nlm.nih.gov/pubmed/23840660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067314
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