Pre-B cell receptor–mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC

Initial cell surface expression of the pre-B cell receptor induces proliferation. After 2 to 5 divisions, however, large pre-BII (Fraction C') cells exit cell cycle to become resting, small pre-BII cells (Fraction D). The mechanism by which pre-BII cells exit cell cycle, however, is currently u...

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Dettagli Bibliografici
Autori principali: Nahar, Rahul, Ramezani-Rad, Parham, Mossner, Maximilian, Duy, Cihangir, Cerchietti, Leandro, Geng, Huimin, Dovat, Sinisa, Jumaa, Hassan, Ye, B. Hilda, Melnick, Ari, Müschen, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204735/
https://ncbi.nlm.nih.gov/pubmed/21856866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-331181
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