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BACH2-BCL6 balance regulates selection at the pre-BCR checkpoint
At the pre-B cell receptor (pre-BCR) checkpoint, developing pre-B cells are selected for successful rearrangement of V(H)-DJ(H) gene segments and expression of a pre-BCR. Reduced stringency at this checkpoint may obstruct the B cell repertoire with non-functional B cell clones. Earlier studies descr...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943645/ https://ncbi.nlm.nih.gov/pubmed/24332591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2013.11.002 |
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