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Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy

Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates and are difficult to study in vitro. Cells cultured as monolayers typically exhibit less resistance to therapy than those grown in vivo. Therefore, it is important to develop an alternative researc...

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Bibliografske podrobnosti
Main Authors: Phung, Yen T., Barbone, Dario, Broaddus, V. Courtney, Ho, Mitchell
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204399/
https://ncbi.nlm.nih.gov/pubmed/22043235
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