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Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy
Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates and are difficult to study in vitro. Cells cultured as monolayers typically exhibit less resistance to therapy than those grown in vivo. Therefore, it is important to develop an alternative researc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Ivyspring International Publisher
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204399/ https://ncbi.nlm.nih.gov/pubmed/22043235 |
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