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Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy

Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates and are difficult to study in vitro. Cells cultured as monolayers typically exhibit less resistance to therapy than those grown in vivo. Therefore, it is important to develop an alternative researc...

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Hlavní autoři: Phung, Yen T., Barbone, Dario, Broaddus, V. Courtney, Ho, Mitchell
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204399/
https://ncbi.nlm.nih.gov/pubmed/22043235
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