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Bcl-2 Family Proteins Contribute to Apoptotic Resistance in Lung Cancer Multicellular Spheroids

Combinatorial therapies using the proteasome inhibitor, bortezomib, have been found to induce synergistic apoptosis in cancer cells grown as monolayers; however, three-dimensional spheroid culture may be a better model for the multicellular resistance found in solid tumors, such as lung cancer. We t...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Yang, Tsung-Ming, Barbone, Dario, Fennell, Dean A., Broaddus, V. Courtney
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Thoracic Society 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701959/
https://ncbi.nlm.nih.gov/pubmed/19097992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0320OC
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