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Bcl-2 Family Proteins Contribute to Apoptotic Resistance in Lung Cancer Multicellular Spheroids

Combinatorial therapies using the proteasome inhibitor, bortezomib, have been found to induce synergistic apoptosis in cancer cells grown as monolayers; however, three-dimensional spheroid culture may be a better model for the multicellular resistance found in solid tumors, such as lung cancer. We t...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yang, Tsung-Ming, Barbone, Dario, Fennell, Dean A., Broaddus, V. Courtney
פורמט: Artigo
שפה:Inglês
יצא לאור: American Thoracic Society 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701959/
https://ncbi.nlm.nih.gov/pubmed/19097992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0320OC
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